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SARM - Selective Androgen Receptor Modulators

Non-steroidal compounds that, by binding with androgen receptors in tissues, are designed not only to stimulate the growth of lean muscle mass or to support the reduction of unwanted adipose tissue. They can also support the mineralization of bone tissue - a solid base on which muscle fibers are attached. In addition, you can count on an increase in strength, endurance and performance of the body.

Ostarine - Mk 2866

Chemical Formula C19H14F3N3O3

IUPAC Name

N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide

Testolone - RAD140

Chemical Formula C20H16ClN5O2

IUPAC Name

2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile

ACP-105

Chemical Formula C16H19ClN2O

IUPAC Name

2-Chloro-4-[(1R,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]-3-methylbenzonitrile

Andarine - S4

Chemical Formula C19H18F3N3O6

IUPAC Name

(2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

YK-11

Chemical Formula C25H34O6

IUPAC Name

(20E)-17α,20-[(1-methoxyethylidene) bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid, methyl ester

AC-262,356

Chemical Formula C18H18N2O

IUPAC Name

4-[(1R,3S,5S)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile

Ligandrol - LGD 4033

Chemical Formula C14H12F6N2O

IUPAC Name

4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxyethyl) pyrrolidin-1-yl)-2 (trifluoromethyl) benzonitrile

S-23

Chemical Formula C18H13ClF4N2O3

IUPAC Name

(2S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide

Selective Androgen Receptor Modulators (SARMs) are synthetic compounds designed to interact selectively with androgen receptors in body tissues such as muscles and bones, aiming to achieve specific anabolic effects without causing undesirable androgenic side effects associated with traditional anabolic steroids. SARMs operate through a combination of mechanisms, including gene transcription activation and protein synthesis regulation. By binding to androgen receptors, SARMs can enhance the expression of genes related to muscle growth and repair, leading to an increase in muscle mass and strength. While SARMs exhibit greater selectivity compared to anabolic steroids, their activity may vary depending on the type of SARM and the tissue in which they are activated. Research surrounding SARMs aims to optimize this selectivity to maximize anabolic benefits while minimizing potential adverse effects, making them of interest in fields such as muscle wasting therapy, osteoporosis, and other conditions related to muscle mass and bone density. However, it is crucial to note that research on SARMs is still in its early stages, and their safety and efficacy in humans must be thoroughly evaluated before widespread use.

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